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Table 2 HML10 sequences estimated time of integration

From: Identification of a novel HERV-K(HML10): comprehensive characterization and comparative analysis in non-human primates provide insights about HML10 proviruses structure and diffusion

  LTR vs LTR LTR vs consensus gag vs consensus pol vs consensus a env vs consensus b Average O.C.A. c
1p36.13 14.1 21.0 22.5 no pol (62 nt only) 31.9 22.4 rhesus
1p22.2 no 5′ and 3’LTRs no 5′ and 3’LTRs no gag no pol 45.0 45.0 rhesus
1q22 14.7 44.1 35.7 28.9 32.7 31.2 rhesus
6p22.1 12.7 36.5 43.0 18.9 32.8 28.8 rhesus
6p21.33a 22.9 18.0 25.2 21.3 21.3 21.7 rhesusd
6p21.33b 22.9 18.0 25.2 21.3 21.3 21.7 orangutand
6q22.31 17.2 38.8 38.9 44.8 35.1 35.0 rhesus
19p13.2 no 5′ and 3’LTRs no 5′ and 3’LTRs e 20.8 no env (48 nt only) 20.8 rhesus
19q13.41 no 3’LTR 46.0 37.4 27.2 45.9 39.1 rhesus
Yq11.221 20.8 45.2 41.5 30.4 44.7 36.5 rhesus
Average 17.9 33.5 33.7 26.7 34.5 28,58  
  1. apartial sequence: nucleotides 1277–2571 in LTR14-HERVKC4-LTR14
  2. bpartial sequence: nucleotides 4103–5810 in LTR14-HERVKC4-LTR14
  3. cOldest Common Ancestor
  4. dProvirus loss in various intermediate species: chimpanzee, gorilla, orangutan and gibbon (6p21.33a); chimpanzee, gorilla, gibbon and rhesus (6p21.33b)
  5. esequence showing an highly divergent gag sequence, giving an estimated T of 165,7 that was not taken into account for the final T calculation